| ncRNA name | rno-miR-29b |
| ncRNA Category | miRNA |
| Disease name | diabetic retinopathy (DR) |
| Species | Rattus norvegicus |
| Tissues/Cell_line | retinas |
| Methods | immunofluorescence, in situ hybridization, qRT-PCR, Western blot, luciferase reporter assay |
| Expression pattern | up-regulated |
| Functional description | RAX expression may be indirectly regulated by miR-29b, and the upregulation of this miRNA at the early stage of STZ-induced diabetes may have a protective effect against the apoptosis of RGCs and cells of the INL by the pro-apoptotic RNA-dependent protein kinase (PKR) signaling pathway. |
| PubMed ID | 21897745 |
| Year | 2011 |
| Title | Expression and cellular localization of microRNA-29b and RAX, an activator of the RNA-dependent protein kinase (PKR), in the retina of streptozotocin-induced diabetic rats. |
| Drug-related ncRNA | NO |
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